Respiratory Infections

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Respiratory Infections


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Causative Agent

A total of 31 distinct echovirus serotypes are known to infect humans. Although the majority of infections are asymptomatic, disease when it does occur depends on the age, gender and immune status of the host, as well as the subgroup and serotype of the infecting strain.

Clinical Description

Non-polio enteroviruses, which include all Coxsackieviruses and Echoviruses, constitute a major subgroup of small RNA viruses (picornaviruses) that readily infect and are shed from the lower digestive tract. Initially it was believed that these agents primarily caused mild acute aseptic meningitis syndromes, pleurodynia, exanthems, pericarditis, non-specific febrile illness and occasional fulminant encephalomyocarditis of the newborn. It is now apparent that their spectrum of disease is much broader; there may be permanent sequelae and some infections may trigger chronic active disease processes.


Although echoviruses, like all other enteroviruses, are predominantly organisms of the gastrointestinal tract with transmission by the faecal oral route. Where hygiene standards are adequate to prevent this, limited transmission can still take place via the respiratory route.

Surveillance in Scotland

Regional virus labs report confirmed cases to HPS. While the numbers of cases reported via this route will be a gross underestimate of the levels of infection, it remains a useful means of monitoring the predominant types of Echovirus in circulation, as well as identifying outbreaks.

Trends in Scotland (1995-2000)

Numbers of echovirus reports to HPS have been at low levels (200 or less per year) since 1990 when there were a large number of reports. A shift in the predominant types is apparent for 2000, with types 13, 18 and 30 accounting for most infections compared with types 4, 9 and 11 throughout the 1990's.

Incidence and Risk

Since the vast majority of echovirus infections are asymptomatic, it is difficult to determine what the true incidence of infection might be. A common cause of summer respiratory infections in children, they occur with a higher prevalence in summer and autumn months.


The predominantly mild symptoms and the ubiquitous nature of these infections, means that preventative measures are not usually necessary or recommended.

Graph displaying echovirus comparison of major types reported to SCIEH/HPS: 1990-1999 vs 2000