COVID-19 - EAVE II Study


Current applied health service research to inform the public health response

Public Health Scotland (PHS) is collaborating with some Scottish Universities on the EAVE-II study which will track the progress of the Covid-19 pandemic in near real-time across Scotland. It will also find out important risk factors for COVID-19 and look at how well possible treatments, such as vaccines work.

Why it is called EAVE-II

EAVE stands for "Early Assessment of Vaccine and anti-viral Effectiveness." This was a previous study that looked at how well vaccinations worked for swine flu. The current study builds on this work and applies this to the current COVID-19 epidemic.

What the study will do

Provide real-time monitoring of the COVID-19 epidemic in Scotland. This will help to inform the government on special public health measures such as lock-down and social distancing.

Find out the risk of COVID-19 to the whole population, groups of people, and different areas of the country. This will allow us to protect those people who are most vulnerable to COVID-19.

Pregnant women form one of the groups. The results of examining outcomes for women and their babies will inform the care of pregnant women with COVID-19 infection.

Discover which treatments and public health measures are effective for preventing and treating infection, including vaccination once this is available.

What data the study will use

EAVE-II will collect electronic data from 5.4 million people living in Scotland. Medical problems will be grouped into broad categories and any data that could identify you will be removed. The remaining data will be securely stored and only the researchers will be able to use it.

This will include information on:

  • medical conditions recorded in GP records, for example, high blood pressure or diabetes
  • medical conditions recorded in out of hours consultations, such as suspected COVID-19 infection
  • COVID-19 test results, including swab results and antibody tests once these become available
  • for antibody testing some individuals, who may or may not have had a diagnosis of COVID19, will have routine blood tests as part of their care, or as blood donors – a random number of these blood samples will be tested for COVID-19
  • prescriptions, such as antibiotics and anti-inflammatory medications
  • use of accident and emergency
  • hospital admissionsm
  • maternity and birth records

How data about me will be kept safe

The PHS privacy notice explains how data is kept safe.